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Epilepsy

Poststroke epilepsy—old definitions fit best

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Cerebrovascular disease is the most frequently identified antecedent of new-onset seizures or epilepsy in industrialized countries. Three recent publications have evaluated the risk of epilepsy following a first cerebrovascular insult. Each report provides evidence for a substantial risk in some patient subgroups, although the study methodologies and definitions of epilepsy vary.

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References

  1. Olafsson, E. et al. Incidence of unprovoked seizures and epilepsy in Iceland and assessment of the epilepsy syndrome classification: a prospective study. Lancet Neurol. 4, 627–634 (2005).

    Article  Google Scholar 

  2. Jungehulsing, G. J., Heuschmann, P. U., Holtkamp, M., Schwab, S. & Kolominsky-Rabas, P. L. Incidence and predictors of post-stroke epilepsy. Acta Neurol. Scand. http://dx.doi.org/10.1111/ane.12070.

  3. Arntz, R. et al. Post-stroke epilepsy in young adults: a long-term follow-up study. PLoS ONE 8, e55498 (2013).

    Article  CAS  Google Scholar 

  4. Graham, N. S., Crichton, S., Koutroumanidis, M., Wolfe, C. D. & Rudd, A. G. Incidence and associations of poststroke epilepsy: the prospective South London Stroke Register. Stroke 44, 605–611 (2013).

    Article  Google Scholar 

  5. Beghi, E. et al. Recommendation for a definition of acute symptomatic seizure. Epilepsia 51, 671–675 (2010).

    Article  Google Scholar 

  6. Hesdorffer, D. C., Benn, E. K., Cascino, G. D. & Hauser, W. A. Is a first acute symptomatic seizure epilepsy? Mortality and risk for recurrent seizure. Epilepsia 50, 1102–1108 (2009).

    Article  Google Scholar 

  7. Thurman, D. J. et al. Standards for epidemiologic studies and surveillance of epilepsy. Epilepsia 52 (Suppl. 7), 2–26 (2011).

    Article  CAS  Google Scholar 

  8. Fisher, R. S. et al. Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia 46, 470–472 (2005).

    Article  Google Scholar 

  9. Easton, J. D. et al. Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke 40, 2276–2293 (2009).

    Article  Google Scholar 

  10. Beghi, E. et al. Incidence and predictors of acute symptomatic seizures after stroke. Neurology 77, 1785–1793 (2011).

    Article  CAS  Google Scholar 

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W. A. Hauser is a consultant to the Federal Aviation Administration and receives grant funding from the Centers for Disease Control and Prevention. He has been a consultant to Neuropace and Eisai Pharmaceuticals, and is a member of a data and safety monitoring board for Teva Pharmaceuticals. He has received travel funding from the International League Against Epilepsy. He has no conflicts in terms of the current paper.

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Hauser, W. Poststroke epilepsy—old definitions fit best. Nat Rev Neurol 9, 305–306 (2013). https://doi.org/10.1038/nrneurol.2013.80

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