The International Multiple Sclerosis (MS) Genetics Consortium has discovered 48 new genetic variants that are associated with increased susceptibility to MS. Using the ImmunoChip genotyping array, which enables fine mapping of immune-related loci, the researchers identified 97 MS-associated single nucleotide polymorphisms, 48 of which were previously unknown. The findings should provide new avenues for exploration of the immune mechanisms underlying MS.
ORIGINAL RESEARCH PAPER
International Multiple Sclerosis Genetics Consortium (IMSGC). Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat. Genet. doi:10.1038/ng.2770
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Genotyping study identifies a plethora of new susceptibility variants for multiple sclerosis. Nat Rev Neurol 9, 601 (2013). https://doi.org/10.1038/nrneurol.2013.219
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DOI: https://doi.org/10.1038/nrneurol.2013.219