Substantial progress has been made over the past four decades in treating the symptoms of Parkinson disease, but treatments that slow its inexorable progression have remained tantalizingly out of reach. New research raises hopes that a means might have been found to safely and effectively slow progression of Parkinson disease and delay its clinical emergence.
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Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson’s disease model
Scientific Reports Open Access 24 June 2019
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R. F. Pfeiffer has received honoraria from Boehringer-Ingelheim, GlaxoSmithKline, Novartis and Teva for lectures and honoraria from Boehringer-Ingelheim, Genactis, Ipsen, Kyowa, Schlesinger Associates, Solvay and Theravance for consulting. He has also received research funding from Boehringer-Ingelheim, Eisai, Kyowa, Novartis, Santhera and Schwarz and honoraria from the Michael J Fox Foundation, Northwestern University and the Parkinson Study Group for acting as a clinical trial site investigator.
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Pfeiffer, R. Calcium channel blockers and Parkinson disease. Nat Rev Neurol 6, 188–189 (2010). https://doi.org/10.1038/nrneurol.2010.31
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DOI: https://doi.org/10.1038/nrneurol.2010.31
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Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson’s disease model
Scientific Reports (2019)