A known nanoparticle-based overall calcification propensity assay, which measures the time taken for primary calciprotein particles (CPPs) to convert to secondary CPPs (T50), has been used to show an association between mortality and graft failure in renal transplant recipients. In the retrospective study, presented in abstract form, patients with short T50 durations—and high serum calcification propensities—had higher risk of all-cause mortality and renal graft failure than those with long T50 durations.
References
Keyzer, C. A. et al. High serum calcification propensity is associated with mortality and graft failure in renal transplant recipients [abstract 4064]. ERA–EDTA Congress [online], (2014).
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Calcification propensity associated with renal graft failure. Nat Rev Nephrol 10, 422 (2014). https://doi.org/10.1038/nrneph.2014.109
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DOI: https://doi.org/10.1038/nrneph.2014.109