Estimating renal function in the normal to high range is challenging, and even more so in critically ill patients. An analysis of commonly used equations for estimating renal function demonstrates that these formulae might not be accurate in this setting, which has important implications for drug dosing.
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Demirjian, S., Poggio, E. Estimating renal function in the ICU: even more challenging. Nat Rev Nephrol 7, 549–550 (2011). https://doi.org/10.1038/nrneph.2011.126
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DOI: https://doi.org/10.1038/nrneph.2011.126