Suzuki and colleagues divided 186 children with nonalcoholic fatty liver disease (NAFLD) into three groups on the basis of their Tanner stage of puberty. Patients who were at or beyond puberty had less severe clinical and histopathologic features of NAFLD, such as steatohepatitis, than patients who had not entered puberty. However, postpubescent patients had a higher prevalence of Mallory–Denk bodies than the other two groups.
ORIGINAL RESEARCH PAPER
Suzuki, A. et al. Association between puberty and features of nonalcoholic fatty liver disease. Clin. Gastroenterol. Hepatol. doi:10.1016/j.cgh.2012.01.020
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The features of nonalcoholic fatty liver disease are affected by puberty stage. Nat Rev Gastroenterol Hepatol 9, 189 (2012). https://doi.org/10.1038/nrgastro.2012.39
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DOI: https://doi.org/10.1038/nrgastro.2012.39