Chronic HCV infection is a leading cause of liver-related morbidity and mortality. In 2011, treatment options for patients infected with HCV genotype 1 changed dramatically with the approval of two nonstructural protein 3 protease inhibitors—boceprevir and telaprevir—by the FDA and the European Medicines Agency.
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W. P. Hofmann has been a speaker for Bristol-Meyers Squibb, Gilead, MSD and Janssen Cilag. W. P. Hofmann has been a speaker for and received grant/research support from Roche. S. Zeuzem has been a consultant for and received grant/research support from Abbott, Achillion, Boehringer Ingelheim, Bristol-Meyers Squibb, Gilead, iTherX, Merck, Pharmasset, Roche, Santaris, Tibotec and Vertex. S Zeuzem has been a speaker for Bristol-Meyers Squibb, Gilead, Merck, Roche, Tibotec and Vertex.
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Hofmann, W., Zeuzem, S. A new standard of care and the race towards IFN-free therapy. Nat Rev Gastroenterol Hepatol 9, 67–68 (2012). https://doi.org/10.1038/nrgastro.2011.249
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DOI: https://doi.org/10.1038/nrgastro.2011.249