A prospective randomized controlled trial in patients with papillary thyroid cancer without lymph node metastases demonstrated similar oncologic outcomes in patients who underwent total thyroidectomy with prophylactic central compartment lymph node dissection (pCCND) and in those who underwent total thyroidectomy without pCCND. However, pCCND was associated with an increased rate of complications.
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Tevis, S., Chen, H. Papillary thyroid cancer—how aggressive should surgery be?. Nat Rev Endocrinol 11, 195–196 (2015). https://doi.org/10.1038/nrendo.2015.13
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DOI: https://doi.org/10.1038/nrendo.2015.13