Total thyroidectomy and subsequent radioiodine ablation improve the outcome of patients with thyroid tumours measuring >1 cm. Best practice guidelines should serve as a basis for clinical decision making in stage I thyroid cancer; however, Haymart et al. report that soft factors, unrelated to clinical presentation, affect the rate of radioiodine ablation.
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References
Haymart, M. R. et al. The relationship between extent of thyroid cancer and use of radioactive iodine. Ann. Surg. http://dx.doi.org/10.1097/SLA.0b013e31826c8915.
Verburg, F. A., Mäder, U., Kruitwagen, C. L., Luster, M. & Reiners, C. A comparison of prognostic classification systems for differentiated thyroid carcinoma. Clin. Endocrinol. (Oxf.) 72, 830–838 (2010).
Trocchi, P. et al. Thyroid cancer surgery in Germany: an analysis of the nationwide DRG statistics 2005–2006. Langenbecks Arch. Surg. 397, 421–428 (2012).
Biermann, M. et al. Guidelines on radioiodine therapy for differentiated thyroid carcinoma: impact on clinical practice. Nuklearmedizin 44, 229–237 (2005).
Dietlein, M., Luyken, W. A., Schicha, H. & Larena-Avellaneda, A. Incidental multifocal papillary microcarcinomas of the thyroid: is subtotal thyroidectomy combined with radioiodine ablation enough? Nucl. Med. Commun. 26, 3–8 (2005).
American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 19, 1167–1214 (2009).
Sawka, A. M. et al. An updated systematic review and commentary examining the effectiveness of radioactive iodine remnant ablation in well-differentiated thyroid cancer. Endocrinol. Metab. Clin. North Am. 37, 457–480 (2008).
Verburg, F. A. No survival difference after successful 131I ablation between patients with initially low-risk and high-risk differentiated thyroid cancer. Eur. J. Nucl. Med. Mol. Imaging 37, 276–283 (2010).
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M. Luster is a consultant to and member of the speaker's bureau of Genzyme Corp. and serves as consultant and advisor for Bayer HealthCare Pharmaceuticals. T. J. Musholt declares no competing interests.
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Luster, M., Musholt, T. Thyroid surgery and radioiodine ablation—the surgeon's role. Nat Rev Endocrinol 9, 140–141 (2013). https://doi.org/10.1038/nrendo.2012.229
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DOI: https://doi.org/10.1038/nrendo.2012.229
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