Data from three phase II trials of tumor-infiltrating lymphocytes demonstrate high and durable complete response rates in patients with stage IV melanoma. Improved clinical outcomes might be achieved by combining tumor-infiltrating lymphocytes with other novel immunotherapeutic agents.
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Chesney, J., McMasters, K. Tumor-infiltrating T cells—ready for prime time in melanoma?. Nat Rev Clin Oncol 8, 449–450 (2011). https://doi.org/10.1038/nrclinonc.2011.103
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DOI: https://doi.org/10.1038/nrclinonc.2011.103