The results of HF-ACTION—the largest ever intervention trial of a nonpharmacological treatment for chronic heart failure—have been reported. The investigators randomly allocated participants to either a structured exercise program or to usual care. Although the primary end point was not reached at the prespecified significance level, the background evidence and data from previous trials and other prespecified analyses compel me to conclude that exercise training should be recommended for patients with stable chronic heart failure.
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Coats, A. Support for exercise training in CHF. Nat Rev Cardiol 6, 447–448 (2009). https://doi.org/10.1038/nrcardio.2009.96
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DOI: https://doi.org/10.1038/nrcardio.2009.96
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