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Stroke

Improving characterization of childhood cerebral arteriopathies

There is notable variation in incidence, presentation, risk factors, and prognosis for strokes occurring in children. At present, there is no stroke classification system specifically tailored to the multiple risk factors and etiologies of pediatric stroke. The study by the International Pediatric Stroke Study investigators on predictors of cerebral arteriopathy in children with arterial ischemic stroke deserves special attention in planning secondary stroke prevention strategies in this population of patients.

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References

  1. Amlie-Lefond, C. et al. Predictors of cerebral arteriopathy in children with arterial ischemic stroke: results of the International Pediatric Stroke Study. Circulation 119, 1417–1423 (2009).

    Article  Google Scholar 

  2. Soper, R. et al. Ischemic stroke and intracranial multifocal cerebral arteriopathy in Williams syndrome. J. Pediatr. 126, 945–948 (1995).

    Article  CAS  Google Scholar 

  3. Amlie-Lefond, C., Sébire, G. & Fullerton, H. J. Recent developments in childhood arterial ischaemic stroke. Lancet Neurol. 7, 425–435 (2008).

    Article  Google Scholar 

  4. Chabrier, S. et al. Transient cerebral arteriopathy: a disorder recognized by serial angiograms in children with stroke. J. Child. Neurol. 13, 27–32 (1998).

    Article  CAS  Google Scholar 

  5. Johnston, M. V. & Comi, A. Acute stroke syndromes. In Nelson Textbook of Pediatrics, 18th edn (eds Kliegman, R. M., Behrman, R. E., Jenson, H. B. & Stanton, B. F) 2508–2511 (WB Saunders, Oxford, 2007).

    Google Scholar 

  6. Braun, K. P. et al. The course and outcome of unilateral intracranial arteriopathy in 79 children with iscaemic stroke. Brain 132, 544–557 (2009).

    Article  CAS  Google Scholar 

  7. Sébire, G. Transient cerebral arteriopathy in childhood. Lancet 368, 8–10 (2006).

    Article  Google Scholar 

  8. Smeeth, L. et al. Risk of myocardial infarction and stroke after acute infection or vaccination. N. Engl. J. Med. 351, 2611–2618 (2004).

    Article  CAS  Google Scholar 

  9. Clayton, T. C., Thompson, M. & Meade, T. W. Recent respiratory infection and risk of cardiovascular disease: case–control study through a general practice database. Eur. Heart J. 29, 96–103 (2008).

    Article  Google Scholar 

  10. Danchaivijitr, N., Cox, T. C., Saunders, D. E. & Ganesan, V. Evolution of cerebral arteriopathies in childhood arterial ischemic stroke. Ann. Neurol. 59, 620–626 (2006).

    Article  Google Scholar 

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Correspondence to Jose Biller.

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Biller, J. Improving characterization of childhood cerebral arteriopathies. Nat Rev Cardiol 6, 395–397 (2009). https://doi.org/10.1038/nrcardio.2009.73

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