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Mitochondria to the rescue

Nature Medicine volume 18, pages 653–654 (2012)Cite this article

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A new study using a mouse model of lung diseases is the first demonstration in vivo that bone marrow–derived stromal cells can repair tissue injury through the transfer of mitochondria (pages 751–758). This suggests that rescue of injured cells through mitochondrial transfer may be an important process in many diseases.

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Figure 1: Mitochondrial transfer from BMSCs protects against lung injury.

References

  1. Wolf, P. Br. J. Haematol. 13, 269–288 (1967).

    Article  CAS  Google Scholar 

  2. Berckmans, R.J. et al. Arthritis Rheum. 46, 2857–2866 (2002).

    Article  CAS  Google Scholar 

  3. Rak, J. Semin. Thromb. Haemost. 36, 888–906 (2010).

    Article  CAS  Google Scholar 

  4. Meckes, D.G. Jr. & Raab-Traub, N. J. Virol. 85, 12844–12854 (2011).

    Article  CAS  Google Scholar 

  5. Rak, J. Semin. Thromb. Hemost. 36, 888–906 (2010).

    Article  CAS  Google Scholar 

  6. Valadi, H. et al. Nat. Cell Biol. 9, 654–659 (2007).

    Article  CAS  Google Scholar 

  7. Quesenberry, P.J. & Aliotta, J.M. Adv. Drug Deliv. Rev. 62, 1141–1148 (2010).

    Article  CAS  Google Scholar 

  8. Islam, M.N et al. Nat. Med. 18, 759–765 (2012).

    Article  CAS  Google Scholar 

  9. Gupta, N. et al. J. Immunol. 179, 1855–1863 (2007).

    Article  CAS  Google Scholar 

  10. Prockop, D.J. & Oh, J.Y. J. Cell Biochem. 113, 1460–1469 (2012).

    CAS  Google Scholar 

  11. Spees, J.L. et al. Proc. Natl. Acad. Sci. USA 103, 1283–1288 (2006).

    Article  CAS  Google Scholar 

  12. Plotnikov, E.Y. et al. J. Cell Mol. Med. 12, 1622–1631 (2008).

    Article  CAS  Google Scholar 

  13. Cho, Y.M. et al. PLoS ONE 7, e32778 (2012).

    Article  CAS  Google Scholar 

  14. Rebbeck, C.A., Leroi, A.M. & Burt, A. Science 331, 303 (2011).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Darwin J. Prockop is Director of the Texas A&M Health Science Center College of Medicine Institute for Regenerative Medicine at Scott & White, Temple, Texas, USA.,

    Darwin J Prockop

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  1. Darwin J Prockop
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Correspondence to Darwin J Prockop.

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D.J.P. is the chairman of the Scientific Advisory Board of Temple Therapeutics, LLC.

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Prockop, D. Mitochondria to the rescue. Nat Med 18, 653–654 (2012). https://doi.org/10.1038/nm.2769

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