New data show that integrin signaling by the Syk tyrosine kinase requires adaptors, such as DAP12, that have immunoreceptor tyrosine-based activation motifs.
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Kim Caesar
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Kahn, M., Koretzky, G. Integrins and ITAMs: more than just good neighbors. Nat Immunol 7, 1286–1288 (2006). https://doi.org/10.1038/ni1206-1286
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DOI: https://doi.org/10.1038/ni1206-1286
