How individual hematopoietic stem cells contribute to blood cell formation throughout a lifetime has remained a subject of debate. A new analysis suggests there is substantial variation in hematopoietic stem cell fate and self-renewal activity.
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Crooks, G., Weinberg, K. The unpredictable stem cell. Nat Immunol 7, 1129–1130 (2006). https://doi.org/10.1038/ni1106-1129
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DOI: https://doi.org/10.1038/ni1106-1129