The mechanisms responsible for establishing allelic exclusion remain enigmatic. New data indicate that stochastic interactions of antigen-receptor alleles with repressive nuclear compartments may contribute to the mechanisms that support allelic exclusion.
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Katie Ris-Vicari
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Murre, C. Nuclear geography and allelic exclusion. Nat Immunol 9, 718–720 (2008). https://doi.org/10.1038/ni0708-718
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DOI: https://doi.org/10.1038/ni0708-718
