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NK cell development: Gas matters

The mechanisms governing natural killer cell development are not well understood. Activation of the tyrosine kinase receptors Tyro3, Axl and Mer on pre–natural killer cells by stromal cell–produced ligands now seems to be critical.

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Figure 1: TAM receptors and NK cell development.

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Walzer, T., Vivier, E. NK cell development: Gas matters. Nat Immunol 7, 702–704 (2006). https://doi.org/10.1038/ni0706-702

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