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Preventing injury from within, using selective cPLA2 inhibitors

The enzyme cPLA2 plays a pivotal role in adult respiratory distress syndrome (ARDS). Specific blocking of cPLA2 may present a useful therapeutic target for treating ARDS.

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Figure 1: Diffuse lung injury in ARDS.

Bob Crimi

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Serhan, C. Preventing injury from within, using selective cPLA2 inhibitors. Nat Immunol 1, 13–15 (2000). https://doi.org/10.1038/76865

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