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Revival of the autoantibody model in rheumatoid arthritis

Nature Immunology volume 3, pages 342–344 (2002)Cite this article

Abstract

New evidence revives the old idea that B cells are the principal effectors in rheumatoid arthritis: autoantibodies against a ubiquitous antigen cause joint-specific disease. The resolution of these conflicting hypotheses resides in the joint itself. “

(On-Ko-Chi-Shin) the new idea resides within the old.”

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Figure 1: The tissue determines the disease specificity of autoimmunity.

Bob Crimi

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Authors and Affiliations

  1. Department of Molecular Oncology, Osaka University Graduate School of Medicine. Laboratory for Cytokine Signaling, RIKEN Research Center for Allergy and Immunology, Osaka, 565-0871, Japan

    Toshio Hirano

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  1. Toshio Hirano
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Hirano, T. Revival of the autoantibody model in rheumatoid arthritis. Nat Immunol 3, 342–344 (2002). https://doi.org/10.1038/ni0402-342

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