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Basophils: in the spotlight at last

Nature Immunology volume 9, pages 223–225 (2008)Cite this article

Basophils have long been suspected to be potent inducers of T helper type 2 differentiation. Sokol and colleagues now demonstrate that basophils are required for adoption of the T helper type 2 fate in vivo in response to allergens with protease activity.

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Figure 1: Model of basophil-mediated TH2 differentiation.

Katie Ris-Vicari

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Authors and Affiliations

  1. Booki Min is in the Department of Immunology at the Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.,

    Booki Min

  2. William E. Paul is with the Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. wpaul@niaid.nih.gov,

    William E Paul

Authors
  1. Booki Min
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  2. William E Paul
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Min, B., Paul, W. Basophils: in the spotlight at last. Nat Immunol 9, 223–225 (2008). https://doi.org/10.1038/ni0308-223

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