The chemokine receptor CCR2 was believed to 'summon' infiltrating CCR2+ monocytes into the spleen. Instead, CCR2 seems to be important for 'release' of these cells from bone marrow niches.
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Katie Ris
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Rollins, B. Release the hounds! A chemokine elicits monocytes from bone marrow. Nat Immunol 7, 230–232 (2006). https://doi.org/10.1038/ni0306-230
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DOI: https://doi.org/10.1038/ni0306-230
