T cell receptor activation requires the membrane-associated guanylate kinase CARMA1. A new study finds that a second such kinase, Dlgh1, is also required specifically for activation of the alternative p38 kinase pathway.
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Katie Ris
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Rincón, M., Davis, R. Choreography of MAGUKs during T cell activation. Nat Immunol 8, 126–127 (2007). https://doi.org/10.1038/ni0207-126
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DOI: https://doi.org/10.1038/ni0207-126
