The function of TRAF3, a member of the family of tumor necrosis factor receptor–associated factors, has remained an enigma. Two recent Nature papers now show that TRAF3 regulates interferon and interleukin 10 production.
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Schneider, K., Benedict, C. & Ware, C. A TRAFfic cop for host defense. Nat Immunol 7, 15–16 (2006). https://doi.org/10.1038/ni0106-15
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DOI: https://doi.org/10.1038/ni0106-15
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