Until now, the function of OX2 has been unclear. Now, with the cloning of its receptor and the generation of OX2−/− mice, a possible role as an inhibitor for myeloid activation has emerged.
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Nathan, C., Muller, W. Putting the brakes on innate immunity: a regulatory role for CD200?. Nat Immunol 2, 17–19 (2001). https://doi.org/10.1038/83124
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DOI: https://doi.org/10.1038/83124