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Regulation of mRNA Utilization and Degradation by Amino-acid Starvation

Nature New Biology volume 232, pages 165–169 (1971)Cite this article

Abstract

Amino-acid starvation of a stringent strain of E. coli relieves the polar effect on distal messenger RNA imposed by a nonsense mutation. There is no relief of polarity starvation of a relaxed strain. In fact, starvation of a relaxed (but not of a stringent) strain by itself causes an artificial polar effect on distal mRNA. These findings are consistent with a mechanism for polarity based on mRNA degradation.

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Authors and Affiliations

  1. Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, 02115

    DANIEL E. MORSE & MIREILLE GUERTIN

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  1. DANIEL E. MORSE
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  2. MIREILLE GUERTIN
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MORSE, D., GUERTIN, M. Regulation of mRNA Utilization and Degradation by Amino-acid Starvation. Nature New Biology 232, 165–169 (1971). https://doi.org/10.1038/newbio232165a0

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  • DOI: https://doi.org/10.1038/newbio232165a0

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