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Should men with serum PSA levels of 4.0 ng/ml or less undergo a prostate biopsy?

Nature Clinical Practice Urology volume 1, pages 12–13 (2004)Cite this article

boxed-textThompson IM et al. (2004) Prevalence of prostate cancer among men with a prostate-specific antigen level ≤4.0 ng per milliliter. N Engl J Med 350: 2239–2246

The 4.0 ng/ml PSA threshold has been challenged; more frequent use of age-specific PSA reference ranges and isoforms should be encouraged, and the need for biopsy determined on a case-by-case basis

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Acknowledgements

The synopsis was written by Suzanne Farley, Associate Editor, Nature Clinical Practice.

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  1. Department of Urology,

    J Brantley Thrasher

  2. University of Kansas Medical Center,

    J Brantley Thrasher

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  1. J Brantley Thrasher
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Correspondence to J Brantley Thrasher.

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Thrasher, J. Should men with serum PSA levels of 4.0 ng/ml or less undergo a prostate biopsy?. Nat Rev Urol 1, 12–13 (2004). https://doi.org/10.1038/ncpuro0013

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