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References
Bubley GJ et al. (1999) Eligibility and response guidelines for phase II trials in androgen-independent prostate cancer: recommendations from the Prostate-Specific Antigen Working Group. J Clin Oncol 17: 3461–3467
Peehl DM (2001) Basic science of hormonal therapy for prostate cancer. Rev Urol 3 (Suppl 3): S15–S22
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Acknowledgements
The synopsis was written by Petra Roberts, Associate Editor, Nature Clinical Practice.
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Dr Berry is a speaker for Aventis.
Glossary
- CR; COMPLETE RESPONSE
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Normalization of PSA to <4 ng/ml confirmed for 1 month
- PR; PARTIAL RESPONSE
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A 50% fall in PSA maintained for 4 weeks
- SD; STABLE DISEASE
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PSA levels which do not rise by >25% or fall by >50% over 8 weeks
- PD; DATE OF PROGRESSION
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Date of first CT scan to show new lesions or 25% increase in previously measured disease, or date of first sustained rise in PSA
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Berry, W. Re-induction of hormonal sensitivity in hormone-refractory prostate cancer—fact or fiction?. Nat Rev Clin Oncol 2, 180–181 (2005). https://doi.org/10.1038/ncponc0136
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DOI: https://doi.org/10.1038/ncponc0136