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Should patients with relapsing multiple sclerosis be given a higher dose and frequency of interferon-β1a?

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References

  1. Panitch H et al. (2002) Randomized, comparative study of interferon beta-1a treatment regimens in MS: The EVIDENCE Trial. Neurology 59: 1496–1506

    Article  CAS  Google Scholar 

  2. Rask C et al. (online 7 March 2002) Comparative study of Rebif to Avonex and orphan exclusivity. [http://www.fda.gov/cder/biologics/review/ifnbser030702r1.pdf] (accessed 6 July 2005)

    Google Scholar 

  3. de la Fuente-Fernández R et al. (2001) Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease. Science 293: 1164–1166

    Article  Google Scholar 

  4. Wager TD et al. (2004) Placebo-induced changes in FMRI in the anticipation and experience of pain. Science 303: 1162–1167

    Article  CAS  Google Scholar 

  5. Francis GS et al. (2005) Interferon β-1a in MS: results following development of neutralizing antibodies in PRISMS. Neurology 65: 48–55

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Emma Campbell, Associate Editor, Nature Clinical Practice.

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Correspondence to Robert J Fox.

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Drs Fox and Rudick have received grant support or honoraria for speaking and consulting services in the past 3 years from Accorda Therapeutics, Biogen Idec, Centocor, Merck, Millenium, National Institutes Of Health, National Multiple Sclerosis Society, Questcor, Serono, Teva Neuroscience and Vertex Pharmaceuticals.

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Fox, R., Rudick, R. Should patients with relapsing multiple sclerosis be given a higher dose and frequency of interferon-β1a?. Nat Rev Neurol 1, 16–17 (2005). https://doi.org/10.1038/ncpneuro0041

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