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Prevalence of fractures in women with rheumatoid arthritis and/or systemic lupus erythematosus on chronic glucocorticoid therapy
BMC Musculoskeletal Disorders Open Access 15 October 2015
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References
LoCascio V et al. (1990) Bone loss in response to long-term glucocorticoid therapy. Bone Miner 8: 39–51
Van Staa TP et al. (2003) Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy. Arthritis Rheum 48: 3224–3229
Weinstein RS et al. (1998) Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids: potential mechanisms of their deleterious effects on bone. J Clin Invest 102: 274–282
O'Brien CA et al. (2004) Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength. Endocrinology 145: 1835–1841
Weinstein RS (2001) Glucocorticoid-induced osteoporosis. Rev Endocr Metab Disord 2: 65–73
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The synopsis was written by Vicky Heath, Associate Editor, Nature Clinical Practice.
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Weinstein, R. Is long-term glucocorticoid therapy associated with a high prevalence of asymptomatic vertebral fractures?. Nat Rev Endocrinol 3, 86–87 (2007). https://doi.org/10.1038/ncpendmet0372
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DOI: https://doi.org/10.1038/ncpendmet0372
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