Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Clinical Advance
  • Published:

Are pediatricians responsible for prevention of adult cardiovascular disease?

Abstract

Atherosclerosis begins in childhood with fatty streaks, which progress seamlessly to fibrous plaques in adulthood. These plaques, in turn, might rupture and cause thrombotic arterial occlusion and ischemic damage to vital organs. The earliest stages and progression of atherosclerosis in youth are influenced by the same major established risk factors for this condition in adults—dyslipidemia, hypertension, smoking, obesity, and diabetes mellitus. Controlling these risk factors at any age is beneficial, but the earlier primary prevention begins, the better the result. As recommended by the American Academy of Pediatrics, pediatricians should support both control and prevention of these risk factors in children via lifestyle modification. Drug treatment can be used to supplement lifestyle modification in the few cases of children with genetic dyslipidemias who do not respond to diet changes. Ultimately, however, effective prevention of adult disease requires a massive cultural change.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. McGill HC Jr et al. (1963) Natural history of human atherosclerotic lesions. In Atherosclerosis and its Origin, 39–65 (Eds Sandler M and Bourne GH) New York: Academic Press

    Google Scholar 

  2. American Academy of Pediatrics, Committee on Nutrition (1972) Childhood diet and coronary heart disease. Pediatrics 49: 305–307

  3. American Academy of Pediatrics, Committee on Nutrition (1983) Toward a prudent diet for children. Pediatrics 71: 78–80

  4. American Academy of Pediatrics, Committee on Nutrition (1986) Prudent life-style for children: dietary fat and cholesterol. Pediatrics 78: 521–525

  5. McGill HC Jr et al. (2008) Preventing heart disease in the 21st century: implications of the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study. Circulation 117: 1216–1227

    Article  Google Scholar 

  6. Council on Sports Medicine and Fitness and Council on School Health (2006) Active healthy living: prevention of childhood obesity through increased physical activity. Pediatrics 117: 1834–1842

  7. Daniels SR et al. (2008) Lipid screening and cardiovascular health in childhood. Pediatrics 122: 198–208

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Henry C McGill.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

McGill, H., McMahan, C. & Gidding, S. Are pediatricians responsible for prevention of adult cardiovascular disease?. Nat Rev Cardiol 6, 10–11 (2009). https://doi.org/10.1038/ncpcardio1389

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpcardio1389

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing