Three newly identified endogenous ligands of the nuclear receptor PPARα—hydroxydimethylbutyrate, hexadecanamide and octadecenamide—are implicated in the noncanonical activity of PPARα in synaptic function and hippocampal plasticity.
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Burris, T. PPARα ligands make memories. Nat Chem Biol 12, 993–994 (2016). https://doi.org/10.1038/nchembio.2241
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DOI: https://doi.org/10.1038/nchembio.2241
