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Redox control

A black hole for oxidized glutathione

There is a considerable amount of oxidized glutathione in living cells, yet it is virtually absent from the cytosol. The mystery of where it resides has now been solved. A study in baker's yeast revealed that oxidized glutathione is selectively stashed in vacuoles.

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Figure 1: A new star in redox homeostasis.

Katie Vicari

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Correspondence to Ursula Jakob.

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Winther, J., Jakob, U. A black hole for oxidized glutathione. Nat Chem Biol 9, 69–70 (2013). https://doi.org/10.1038/nchembio.1161

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