There is a considerable amount of oxidized glutathione in living cells, yet it is virtually absent from the cytosol. The mystery of where it resides has now been solved. A study in baker's yeast revealed that oxidized glutathione is selectively stashed in vacuoles.
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Winther, J., Jakob, U. A black hole for oxidized glutathione. Nat Chem Biol 9, 69–70 (2013). https://doi.org/10.1038/nchembio.1161
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DOI: https://doi.org/10.1038/nchembio.1161