Compound 2a

(E)-N-Benzylidene-4-chloroaniline

From: Highly enantioselective trapping of zwitterionic intermediates by imines

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InChIKey NWCAQYVAHZWHIO-XNTDXEJSSA-N

Synonyms:
  • 4-Chloro-N-(phenylmethylene)benzeneamine,
  • 4-chloro-N-[(1E)-phenylmethylene]aniline,
  • p-chlorobenzylidene-phenyl-amine,
  • 4-Chloro-N-[(E)-phenylmethylene]aniline,
  • N-(4-chlorophenyl)-1-phenylmethanimine,
  • N1-benzylidene-4-chloroaniline

Synthetic procedure: See article for the definitive version of this procedure and for full experimental details.

Aldimine 2a was prepared from condensation of the corresponding aromatic aldehyde with the corresponding aniline according to the literature method (Shiino M. and Watanabe, Y. Synthesis of N-substituted N-nitrosohydroxylamines as inhibitors of Mushroom Tyrosinase, Umezawa, K. Bioorg. Med. Chem. 9, 1233-1240 (2001))