α-catenin exists as part of the cadherin–catenin adhesion complex as well as in a cytoplasmic pool. However, which of these pools is responsible for its biological impact remains controversial. A structure-function analysis in Drosophila melanogaster illuminates how the molecular properties of α-catenin translate into functional outcomes in an intact organism.
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Han, SP., Yap, A. An α-catenin déjà vu. Nat Cell Biol 15, 238–239 (2013). https://doi.org/10.1038/ncb2700
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DOI: https://doi.org/10.1038/ncb2700
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