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Regulating intraflagellar transport

Nature Cell Biology volume 14, pages 904–906 (2012)Cite this article

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Kinesin-2 motors mediate anterograde intraflagellar transport (IFT) of IFT particles from the ciliary base to its tip, where particles are remodelled before retrograde transport by dynein 2 motors. Bardet-Biedl syndrome (BBS) and IFT-A proteins are now implicated in regulation of IFT assembly at the ciliary base and tip.

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Figure 1: Two different models for IFT in C. elegans.

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Authors and Affiliations

  1. Lotte B. Pedersen and Søren T. Christensen are in the Department of Biology, University of Copenhagen, Universitetsparken 13, DK-2100 Copenhagen, Denmark,

    Lotte B. Pedersen & Søren T. Christensen

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  1. Lotte B. Pedersen
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  2. Søren T. Christensen
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Correspondence to Lotte B. Pedersen.

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The authors declare no competing financial interests.

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Pedersen, L., Christensen, S. Regulating intraflagellar transport. Nat Cell Biol 14, 904–906 (2012). https://doi.org/10.1038/ncb2569

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