Recognition of apoptotic cells by phagocytic cells in Caenorhabditis elegans has been something of a mystery. A secreted transthyretin-like protein, TTR-52, has been identified as a bridging molecule between apoptotic cells and CED-1 on the phagocytic cells that engulf them.
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Rutkowski, R., Gartner, A. Tagging the dead: a bridging factor for Caenorhabditis elegans phagocyte receptors. Nat Cell Biol 12, 638–640 (2010). https://doi.org/10.1038/ncb2077
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DOI: https://doi.org/10.1038/ncb2077
