Cell duplication requires the coordination of nuclear division with diverse cellular morphogenesis events, such as cell wall growth. A novel checkpoint has been identified in yeast that coordinates these two events. Unexpectedly, the dynein-activating dynactin complex, but not dynein itself, is an essential component of this checkpoint mechanism.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Suzuki, M. et al. Nature Cell Biol. 6, 861–871 (2004).
Orlean, P. in The Molecular and Cellular Biology of the Yeast Saccharomyces (eds Pringle, J. R., Broach, J. R. & Jones, E. W.) Vol. 3 (Cold Spring Harbor Laboratory, New York, 1997).
Lew, D.J. Curr. Opin. Cell Biol. 15, 648–653 (2003).
Fitch, I. et al. Mol. Biol. Cell 3, 805–818 (1992).
Breeden, L.L. Curr. Biol. 10, R586–R588 (2000).
Pic, A. et al. EMBO J. 19, 1–12 (2000).
Schroer, T.A. Annu. Rev. Cell Dev. Biol. 20, 759–779 (2004).
Adames, N.R. & Cooper, J.A. J. Cell Biol. 149, 863–874 (2000).
Lee, W.-L., Oberle, J.R. & Cooper, J.A. J. Cell Biol. 160, 355–364 (2003).
Sheeman, B. et al. Curr. Biol. 13, 364–372 (2003).
Heinisch, J., Lorberg, A., Schmitz, H.-P. & Jacoby, J. Mol. Microbiol. 32, 671–680 (1999).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hoyt, M. A new checkpoint takes shape. Nat Cell Biol 6, 801–803 (2004). https://doi.org/10.1038/ncb0904-801
Issue Date:
DOI: https://doi.org/10.1038/ncb0904-801