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References
Schlub, T.E., Smyth, R.P., Grimm, A.J., Mak, J. & Davenport, M.P. PLoS Comput. Biol. 6, e1000766 (2010).
Hill, A.J. et al. Nat. Methods 15, 271–274 (2018).
Sack, L.M., Davoli, T., Xu, Q., Li, M.Z. & Elledge, S.J. G3 (Bethesda) 6, 2781–2790 (2016).
Patwardhan, R.P. et al. Nat. Biotechnol. 27, 1173–1175 (2009).
Adamson, B. et al. Cell 167, 1867–1882.e21 (2016).
Datlinger, P. et al. Nat. Methods 14, 297–301 (2017).
Xie, S., Duan, J., Li, B., Zhou, P. & Hon, G.C. Mol. Cell 66, 285–299.e5 (2017).
Dixit, A. et al. Cell 167, 1853–1866.e17 (2016).
Han, K. et al. Nat. Biotechnol. 35, 463–474 (2017).
Shen, J.P. et al. Nat. Methods 14, 573–576 (2017).
Najm, F.J. et al. Nat. Biotechnol. 36, 179–189 (2018).
Boettcher, M. et al. Nat. Biotechnol. 36, 170–178 (2018).
Gasperini, M. et al. Am. J. Hum. Genet. 101, 192–205 (2017).
Du, D. et al. Nat. Methods 14, 577–580 (2017).
Michlits, G. et al. Nat. Methods 14, 1191–1197 (2017).
Feldman, D., Singh, A., Garrity, A.J. & Blainey, P.C. Preprint at bioRxiv https://doi.org/10.1101/262121 (2018).
Lenz, T.L. & Becker, S. Gene 427, 117–123 (2008).
Thompson, J.R., Marcelino, L.A. & Polz, M.F. Nucleic Acids Res. 30, 2083–2088 (2002).
Meyerhans, A., Vartanian, J.P. & Wain-Hobson, S. Nucleic Acids Res. 18, 1687–1691 (1990).
Odelberg, S.J., Weiss, R.B., Hata, A. & White, R. Nucleic Acids Res. 23, 2049–2057 (1995).
Pääbo, S., Irwin, D.M. & Wilson, A.C. J. Biol. Chem. 265, 4718–4721 (1990).
Hegde, M., Strand, C., Hanna, R.E. & Doench, J.G. PLoS One 13, e0197547 (2018).
Judo, M.S., Wedel, A.B. & Wilson, C. Nucleic Acids Res. 26, 1819–1825 (1998).
Zylstra, P., Rothenfluh, H.S., Weiller, G.F., Blanden, R.V. & Steele, E.J. Immunol. Cell Biol. 76, 395–405 (1998).
Sinha, R. et al. Preprint at bioRxiv https://doi.org/10.1101/125724 (2017).
Griffiths, J.A., Richard, A.C., Bach, K., Lun, A.T.L. & Marioni, J.C. Nat. Commun. https://doi.org/10.1038/s41467-018-05083-x (2018).
Costello, M. et al. BMC Genomics 19, 332 (2018).
Kircher, M., Sawyer, S. & Meyer, M. Nucleic Acids Res. 40, e3 (2012).
MacConaill, L.E. et al. BMC Genomics 19, 30 (2018).
Larsson, A.J.M., Stanley, G., Sinha, R., Weissman, I.L. & Sandberg, R. Nat. Methods 15, 305–307 (2018).
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Hanna, R., Doench, J. A case of mistaken identity. Nat Biotechnol 36, 802–804 (2018). https://doi.org/10.1038/nbt.4208
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DOI: https://doi.org/10.1038/nbt.4208
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