Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Viruses leave their stamp on single cells

Nature Biotechnology volume 36, pages 42–44 (2018)Cite this article

Subjects

A method for 'stamping' viruses achieves efficient transduction of single target cells in cultured tissues and in the mouse brain.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Different techniques for single-cell transfection.

Debbie Maizels / Springer Nature

References

  1. Schubert, R. et al. Nat. Biotechnol. https://doi.org/10.1038/nbt.4034 (2017).

    Article  Google Scholar 

  2. Rancz, E.A. et al. Nat. Neurosci. 14, 527–532 (2011).

    Article  CAS  Google Scholar 

  3. Kitamura, K., Judkewitz, B., Kano, M., Denk, W. & Häusser, M. Nat. Methods 5, 61–67 (2008).

    Article  CAS  Google Scholar 

  4. Dempsey, B. et al. Physiol. Rep. 3, e12246 (2015).

    Article  Google Scholar 

  5. Luo, L. Brain Res. Rev. 55, 220–227 (2007).

    Article  CAS  Google Scholar 

  6. DeNardo, L. & Luo, L. Curr. Opin. Neurobiol. 45, 121–129 (2017).

    Article  CAS  Google Scholar 

  7. Packer, A.M., Roska, B. & Häusser, M. Nat. Neurosci. 16, 805–815 (2013).

    Article  CAS  Google Scholar 

  8. Margrie, T.W., Brecht, M. & Sakmann, B. Pflugers Arch. 444, 491–498 (2002).

    Article  CAS  Google Scholar 

  9. Angle, M.R. & Schaefer, A.T. PLoS One 7, e43194 (2012).

    Article  CAS  Google Scholar 

  10. Jonas, E.A., Knox, R.J. & Kaczmarek, L.K. Neuron 19, 7–13 (1997).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ede A. Rancz is at the Cortical Circuits Laboratory, Francis Crick Institute, London, UK.,

    Ede A Rancz

  2. and the Department of Neuroscience, Andreas T. Schaefer is at the Neurophysiology of Behaviour Laboratory, Francis Crick Institute, London, UK, Physiology & Pharmacology, University College London, London, UK.,

    Andreas T Schaefer

Authors
  1. Ede A Rancz
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Andreas T Schaefer
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Ede A Rancz or Andreas T Schaefer.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rancz, E., Schaefer, A. Viruses leave their stamp on single cells. Nat Biotechnol 36, 42–44 (2018). https://doi.org/10.1038/nbt.4043

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt.4043

This article is cited by

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research