Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

Georgiev, I.S. et al. Science 340, 751–756 (2013)

Safety and tolerability of an intratumorally injected DNAzyme, Dz13, in patients with nodular basal-cell carcinoma: a phase 1 first-in-human trial (DISCOVER)

Cho, E. et al. Lancet doi:10.1016/S0140-6736(12)62166-7 (7 May 2013)

Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding

Helwak, A., Kudia, G., Dudnakova, T. & Tollervey, D. Cell 153, 654–665 (2013)

Regeneration and experimental orthotopic transplantation of a bioengineered kidney

Song, J.J. et al. Nat. Med. 19, 646–651 (2013)

A direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration

Wuestefeld, T. et al. Cell 153, 389–401 (2013)