Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Structural and molecular interrogation of intact biological systems

Chung, K. et al. Nature doi:10.1038/nature12107 (10 April 2013)

High-level semi-synthetic production of the potent antimalarial artemisinin

Paddon, C.J. et al. Nature doi:10.1038/nature12051 (10 April 2013)

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells

Rohle, D. et al. Science doi:10.1126/science.1236062 (4 April 2013)

Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation

Wang, F. et al. Science doi:10.1126/science.1234769 (4 April 2013)

X-ray analysis on the nanogram to microgram scale using porous complexes

Inokuma, Y. et al. Nature 495, 461–466 (28 March 2013)

Enzyme-free translation of DNA into sequence-defined synthetic polymers structurally unrelated to nucleic acids

Niu, J. et al. Nat. Chem. 5, 282–292 (3 March 2013)