Abstract
This is a case of a neonate born with a respiratory acidosis with a compensatory metabolic alkalosis. This case demonstrates placental physiology of gas exchange as well as the blunted ventilatory response in the neonate from chronic hypercapnia.
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References
Bavis RW, Mitchell GS . Long-term effect of the perinatal environment on respiratory control. J App Physiol 2008; 104: 1220–1229.
Bavis RW, Mitchell GS . Respiratory plasticity after perinatal hypercapnia in rats. Respir Physiol Neurobiol 2006; 153: 78–91.
Birchard GF, Boggs DF, Tenney SM . Effect of perinatal hypercapnia on the adult ventilatory response to carbon dioxide. Respir Physiol 1984; 57: 341–347.
Creasy RK, Resnik R . Maternal-Fetal Medicine, 4th edn. W.B. Saunders Company: Philadelphia, PA, 1999, pp 260–269, 332-333.
Fraser D, Jensen D, Wolfe L, Hahn P, Davies G . Fetal heart rate response to maternal hypocapnia and hypercapnia in late gestation. J Obstet Gynaecol Can 2008; 30 (4): 312–316.
Ross BD, Post TW . Clinical Physiology of Acid-Base and Electrolyte Disorders, 5th edn. McGraw Hill: New York, 2001, pp 299–363.
Rezzonico R, Mortola JP . Respiratory adaptation to chronic hypercapnia in newborn rates. J App Physiol 1989; 67: 311–315.
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DeLuca, L., Holzman, I. & Gibbs, K. Newborn ventilatory response to maternal chronic hypercapnia. J Perinatol 32, 804–806 (2012). https://doi.org/10.1038/jp.2011.164
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DOI: https://doi.org/10.1038/jp.2011.164