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The impact of improved neonatal intensive care facilities on referral pattern and outcome at a teaching hospital in Ghana

Abstract

Objective:

Evaluate the impact of improved neonatal intensive care facilities on survival and referral patterns at a teaching hospital in Ghana.

Study Design:

Retrospective cohort comparing birth weight-specific survival and referral pattern of newborns requiring intensive care before and after improvement of facilities.

Result:

Improved survival of newborns <2500 g especially those 1000–1499 g (OR=1.74 (CI 1.38–2.20; P<0.00001) for inborn, OR=2.16 (CI 1.36–3.44; P=0.0006) for out-born). Birth asphyxia, the major indication for 2500 g newborn referrals, was associated with reduced survival (OR=0.56 (95% CI 0.40 to 0.78; P=0.0004)). There was fourfold increased referral of out-born 2500 g.

Conclusion:

Improved facilities significantly improved survival of newborns <2500 g, but was of no benefit for newborns 2500 g. A scaling-up approach with investments that improve emergency obstetric services, referral systems, human resources and neonatal resuscitation practices will save more newborn lives.

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References

  1. Saving Newborn Lives. State of the World's Newborns. Save the Children-USA: Washington, DC, 2001.

  2. Hyder A, Morrow R, Wali S, McGuckin J . Burden of Disease for Neonatal Mortality in South Asia and Sub-Saharan Africa. Save the Children Federation-USA: Washington, DC, 2001.

    Google Scholar 

  3. World Health Organization. Pregnancy, Childbirth, Postpartum and Newborn Care: A Guide for Essential Practice. World Health Organization: Geneva, Switzerland, 2003.

  4. Jones G, Steketee RW, Black RE, Bhutta ZA, Morris SS . How many child deaths can we prevent this year? The Bellagio Child Survival Study Group. Lancet 2003; 362: 65–71.

    Article  PubMed  Google Scholar 

  5. Knippenberg R, Lawn JE, Darmstadt GL, Begkoyian G, Fogstad H, Walelign N et al. Lancet Neonatal Survival Steering Team. Systemic scaling up of neonatal care in countries. Lancet 2005; 365 (9464): 1087–1098.

    Article  PubMed  Google Scholar 

  6. Karlsen KA . The S.T.A.B.L.E. Program 2001 Edition.

  7. American Academy of Pediatrics Committee on Fetus and Newborn, American Heart Association Sub-committee on Pediatric Resuscitation, International Liason Committee on Resuscitation Pediatric working group et al. Neonatal Resuscitation Textbook, 4th Edition. United States of America: American Academy of Pediatrics and American Heart Association 2000.

  8. Kattwinkel J, Cook LJ, Hurt H, Short JG, Nowacek GA . Perinatal Continuing Education Program University of Virginia Patent Foundation 2004.

  9. World Health Organization: International Statistical Classification of Diseases. WHO/DIMDI 1994/2006 Chapter XVI, P21.0, P21.1.

  10. Pieper CH, Smith J, Kirsten GF, Malan P . The transport of neonates to an intensive care unit. S Afr Med J 1994; 84 (11 Suppl): 801–803.

    CAS  PubMed  Google Scholar 

  11. Lodé N, Chabernaud JL, Chouakri O, Casadevall I, Maury I, Lagrue E et al. Newborn asphyxia at term during delivery. J Gynecol Obstet Biol Reprod 2003; 32 (Suppl): 1S98–1105.

    Google Scholar 

  12. Callaghan LA, Cartwright DW, O’Rourke P, Davies MW . Infant to staff ratio and risk of mortality in very low birth weight infants. Arch Dis Child Fetal Neonatal Ed 2003; 88: F94–F97.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. International Neonatal Network, Scottish Neonatal Consultants, Nurses Collaborative Study Group. Risk adjusted and population based studies of the outcome for high risk infants in Scotland and Australia. Arch Dis Child Fetal Neonatal Ed 2000; 82: F118–F123.

    Article  Google Scholar 

  14. Were FN, Mukhwana BO, Musoke RN . Neonatal survival of infants less than 2000 g at Kenyatta National Hospital. East Afr Med J 2002; 79 (2): 77–79.

    Article  CAS  PubMed  Google Scholar 

  15. Velaphi SC, Mokhachane M, Mphahlele RM, Beckh-Arnold E, Kuwanda ML, Cooper PA . Survival of very-low-birth-weight infants according to birth weight and gestational age in a public hospital. S Afr Med J 2005; 95 (7): 504–509.

    CAS  PubMed  Google Scholar 

  16. Fanaroff AA, Wright LL, Stevenson DK, Shankaran S, Donovan EF, Ehrenkranz RA et al. Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, May 1991 through December 1992. Am J Obstet Gynecol 1995; 173 (5): 1423–1431.

    Article  CAS  PubMed  Google Scholar 

  17. Owa JA, Osinaike AI . Neonatal morbidity and mortality in Nigeria. Indian J Pediatr 1998; 65 (3): 441–449.

    Article  CAS  PubMed  Google Scholar 

  18. Kinoti SN . Asphyxia of the newborn in east, central and southern Africa. East Afr Med J 1993; 70 (7): 422–433.

    CAS  PubMed  Google Scholar 

  19. Haider BA, Bhutta ZA . Birth asphyxia in developing countries: Current status and public health implications. Curr Probl Pediatr Adolesc Health Care 2006; 36: 178–188.

    Article  Google Scholar 

  20. Bang AT, Bang RA, Baitule S, Deshmukh M, Reddy MH . Burden of morbidities and the unmet need for health care in rural neonates—a prospective observational study in Gadchiroli, India. Indian Pediatr 2001; 38: 952–965.

    CAS  PubMed  Google Scholar 

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Acknowledgements

The authors reviewed the statistics and received no financial support for this work.

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Correspondence to C C Enweronu-Laryea.

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Enweronu-Laryea, C., Nkyekyer, K. & Rodrigues, O. The impact of improved neonatal intensive care facilities on referral pattern and outcome at a teaching hospital in Ghana. J Perinatol 28, 561–565 (2008). https://doi.org/10.1038/jp.2008.61

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