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  • Imaging Case Report
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Extralobar sequestration

Journal of Perinatology volume 29, pages 524–525 (2009)Cite this article

The CT scan showed a soft tissue mass with a vascular supply from the thoracic aorta and venous drainage probably into the hemiazygos vein, creating a vascular stalk or pedicle for the mass. At surgery, the mass was identified and recognized as an extra-lobar sequestration completely separate from the normal trilobed right lobe. The vascular pedicle was isolated showing an artery arising from the thoracic aorta. The venous communication was seen to drain into the hemiazygos vein. These vessels were ligated and the mass easily removed. The pathological specimen showed normal lung tissue with benign bronchiolar epithelium.

Pulmonary sequestrations, first described in 1946 by Pryce1, are a mass of pulmonary tissue sequestered or separated from the normal bronchial connections and with an aberrant blood supply. Classically, a sequestration is thus carried out both from the bronchial tree and the pulmonary artery circulation.1 Sequestrations are believed to arise from supernumerary lung buds that arise from the primitive foregut in about the fifth week of gestation.2, 3 Two types are described: as intralobar sequestration and extralobar sequestration (ELS). Extralobar sequestration comprises ∼25% of all sequestrations and is covered by a separate pleural investment.4 Intralobar sequestration shares a pleural investment with the ipsilateral lung, which may become aerated through the pores of Kohn. The ELS are nonaerated masses.

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References

  1. John PR, Beasley SW, Mayne V . Pulmonary sequestration and related congenital disorders; clinicoradiological review of 41 cases. Pediatr Radidol 1989; 20: 4–9.

    Article  CAS  Google Scholar 

  2. Rosado de Christenson ML, Frazier AA, Stocker JT, Templeton PA . Extralobar sequestration: radiologic–pathologic correlation. RadioGraphics 1993; 13: 425–441.

    Article  CAS  Google Scholar 

  3. Morin C, Filiatrault D, Russo P . Pulmonary sequestration with histologic changes of cystic adenomatoid malformation. Pediatr Radiol 1989; 19: 130–132.

    Article  CAS  Google Scholar 

  4. Felker RE, Tonkin ILD . Imaging of pulmonary sequestration. AJR 1990; 154: 241–249.

    Article  CAS  Google Scholar 

  5. Laje P, Martinez-Ferro M, Grisoni E, Dudgeon D . Intraabdominal pulmonary sequestration. A case series and review of the literature. J Pediatr Surg 2006; 41: 1309–1312.

    Article  Google Scholar 

  6. Benya EC, Bulas DI, Selby DM, Rosenbaum KN . Cystic sonographic appearance of extralobar pulmonary sequestration. Pediatr Radiol 1993; 23: 605–607.

    Article  CAS  Google Scholar 

  7. Sade RM, Clouse M, Ellis FH . The spectrum of pulmonary sequestration. Annals Thoracic Surgery 1974; 18: 644–655.

    Article  CAS  Google Scholar 

  8. Kitano Y, Matsuoka K, Honna T, Kuroda T, Morikawa N, Hayashi S et al. Venous arterialization in extralobar pulmonary sequestration associated with fetal hydrops. J Pediatr Surg 2006; 41: 490–494.

    Article  Google Scholar 

  9. Samuel M, Burge DM . Management of antenatally diagnosed pulmonary sequestration associated with congenital cystic adenomatoid malformation. Thorax 1999; 54: 701–706.

    Article  CAS  Google Scholar 

  10. Stocker JT . Sequestration of the lung. Seminars Diagnostic Pathol 1986; 3: 106–121.

    CAS  Google Scholar 

Download references

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  1. Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USA

    T E Herman & M J Siegel

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  1. T E Herman
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  2. M J Siegel
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Correspondence to T E Herman.

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Herman, T., Siegel, M. Extralobar sequestration. J Perinatol 29, 524–525 (2009). https://doi.org/10.1038/jp.2008.249

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