Summary
Serum samples from eight endogamous Indian tribal populations of Madhya Pradesh (Dhurwa, Halba, Bhatra, Muria, Maria) and Orissa (Deshia Khond, Binjhal, Kisan) with a total of n=731 unrelated individuals were typed for G1M (1,2,3,17), G3M (5,10,11,13,14,15,16,21,26), and KM (1). In seven of these populations five different GM haplotypes were found:GM*1,17;21,26; GM*1,17;10,11,13,15,16; GM*1,2,17;21,26; GM*1,3;5,10,11,13,14,26; andGM*3;5,10,11,13,14,26. In the Kisan sample the haplotypeGM*1,2,17; 21,26 is absent. The intergroup variability in the distribution of these haplotypes is considerable and statistically highly significant. The reasons for that can be attributed to the ethnohistory and to the genetic isolation of these eight endogamous tribal populations. The GM haplotype distribution pattern of all these groups is quite different from that of the non-tribal populations of India, whereas it is in good agreement with that of the so far tested other tribal populations from India. This can be explained by different origin and history of the Indian tribal and non-tribal populations. In the KM system, too, remarkable variability is seen in the distribution of phenotype and allele frequencies among the eight tribal populations under study.
Similar content being viewed by others
Article PDF
References
Bhasin MK, Walter H, Danker-Hopfe H (1992): The distribution of genetical, morphological, and behavioural traits among the people of Indian region (Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, Sri Lanka). Kamla-Raj Enterprises, Delhi
Das K, Roy M, Das MK, Sahu PN, Bhattacharya SK, Malhotra KC, Mukherjee BN, Walter H (1993): Study of the enzyme polymorphisms and haemoglobin patterns among sixteen tribal populations of Central India (Orissa, Madhya Pradesh and Maharashtra). Jpn J Human Genet38: 297–313
Daveau M, Rivat L, Lalouel JM, Langaney A, Roberts DF, Simons MJ (1980): Frequencies of Gm and Km allotypes in the population of Singapore, Sri Lanka, and Punjab in North India. Hum Hered30: 237–244
Field LL, Surje S, Ray AK (1988): Immunoglobulin (GM and KM) allotypes in the Sikh population of India. Am J Phys Anthropol75: 31–35
Fuchs St (1973): The aboriginal tribes of India. The Macmillan Press, London, Basingstoke
Guha BS (1935): Racial affinities of the peoples of India. Census of India 1931. Vol. 1, Part III. The Government of India Press, Simla
Kurczynski TW, Steinberg AG (1967): A general program for maximum likelihood estimation of gene frequencies. Am J Hum Genet19: 178–179
Matsumoto H (1988): Characteristics of Mongoloid and neighbouring populations based on the genetic markers of human immunoglobulins. Hum Genet80: 207–218
Propert DN, Nandan R, Jazwinska EC (1992): GM and KM allotypes and GM RELP allogenotypes in Micronesians from Nauru. Hum Biol64: 17–24
Ray AK, Field LL (1981): Immunoglobulin (Gm) allotypes in a sample of upper-caste Hindus from Bengal, India. Hum Hered31: 358–362
Risley HH (1915): The people of India. Thacker, Spink and Company, Calcutta
Schanfield MS, Gershowitz A (1973): Nonrandom distribution of Gm haplotypes in East Asia. Am J Hum Genet25: 567–574
Schanfield MS, Kirk RL (1981): Further studies on the immunoglobulin allotypes (Gm, Am, and Km) in India. Acta Anthropogen5: 1–21
Steinberg AG (1973): The Gm and Inv immunoglobulin allotypes in Indian populations. A review. In: Sanghvi LD (ed). Population genetics in India. Proc 1st Ann Conf Indian Soc Human Genet Bombay, pp 112–126
Steinberg AG, Cook CE (1981): The distribution of the human immunoglobulin allotypes. Oxford University Press, Oxford
Vos GH, Kirk RL, Steinberg AG (1963): The distribution of the gamma globulin types Gm (a), Gm (b), Gm (x) and Gm (like) in South and South-east Asia and Australia. Am J Hum Genet15: 44–52
Walter H, Matsumoto H, Miyazaki T, Mukherjee BN, Malhotra KC, Das BM, Gilbert K, Lindenberg P (1987): Distribution of Gm and Km allotypes among ten populations of Assam, India. Am J Phys Anthropol73: 439–445
Walter H, Danker-Hopfe H, Bhasin MK (1991): Anthropologie Indiens. Untersuchungen zur genetischen Variabilität der Bevölkerung Indiens mit besonderer Berücksichtigung ihrer regionalen, ethno-sozialen und sprachlichen Gliederung. Gustav Fischer Verlag, Stuttgart, New York
Walter H, Danker-Hopfe H, Eberhardt D, Tegeler M, Das MK, Das K, Bhattacharya SK, Sahu PN, Malhotra KC, Mukherjee BN (1992): Investigations on the variability of blood group polymorphisms among sixteen tribal populations from Orissa, Madyha Pradesh and Maharashtra, India. Z Morphol Anthropol79: 69–94
Walter H, Eberhardt D, Tegeler M, Wiechmann I, Danker-Hopfe H, Bhattacharya SK, Das MK, Mukherjee BN, Das K (1993): HP, GC and PI polymorphism in sixteen central Indian tribal populations. Gene Geography7: 193–202
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Walter, H., Matsumoto, H., Danker-Hopfe, H. et al. GM and KM allotypes in eight tribal populations of madyha Pradesh and Orissa, India. Jap J Human Genet 42, 193–203 (1997). https://doi.org/10.1007/BF02766922
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02766922