As one of the major projects under the “Developmental and Reproductive Research Initiation” organized and sponsored by the Ministry of Science and Technology of China, a national Stem Cell Bank (SCB) network will be established in the coming 4-5 years. Several institutions in Shanghai will collaborate with the teams in Beijing and Guangzhou as well as other cities to make the China SCB a successful network. The key missions of the SCB network include: (1) building a public resources for embryonic stem cells (ESC) supply, mainly hESC, (2) building a platform for developing key stem cell technology and sharing the technology with other scientists in stem cell research, and (3) building a central database and website for information management and sharing to facilitate information and material exchange and research collaboration, within China or internationally. The key components of the plan are the establishment of four stem cell banks in Beijing/Tianjin, Shanghai and Guangzhou to serve North, South and East China, where most of the key Chinese stem cell research scientists live and work at this moment. Later on the service and technical support will cover more area in China. International standards will be employed in the establishment and development of the SCB, including the facilities, the functions, the procedure, quality control and other important issues beyond the science and technology like legal, ethics, service, funding mechanism and so on. The goals for the phase I development of SCB will also include the establishment of some high quality human embryonic stem cell lines, and establishment of training and technique support platform. Efforts for later phase I will focus on promoting the clinical research with stem cell approaches, so that the establishment of clinical grade hESCs will be one of the key focuses. For information sharing, a central database will be developed and the website is currently under construction. International collaboration will be one of the considerations with high priority. Through such collaborations, we can learn from each other share the resources and advantages with other countries.