Abstract
Elevated serum levels of the beta-subunit of human chorionic gonadotrophin (hCG) were measured in 50% of patients with locoregional recurrences or progressive vulvar carcinoma (n = 14). At diagnosis of vulvar cancer, however, the incidence of elevated serum levels was low (5%) in 104 patients. The rising serum levels during progression of disease indicate that the synthesis of the beta-subunit hCG can be increased in vulvar carcinoma.
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de Bruijn, H., ten Hoor, K., Krans, M. et al. Rising serum values of β-subunit human chorionic gonadotrophin (hCG) in patients with progressive vulvar carcinomas. Br J Cancer 75, 1217–1218 (1997). https://doi.org/10.1038/bjc.1997.208
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DOI: https://doi.org/10.1038/bjc.1997.208