Abstract
To evaluate cytotoxic function mediated by killer lymphocytes and macrophages in urological cancer patients, we examined antibody-dependent and spontaneous lympholysis of chicken erythrocyte target cells, which is mediated by macrophages. Our results demonstrate a discordance between cytotoxic mechanisms in cancer patients, killer-cell function being impaired whilst macrophage-mediated cytotoxicity was increased.
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Ratliff, T., McCool, R. & Catalona, W. Antibody-dependent and spontaneous lympholysis in urologic cancer patients. Br J Cancer 39, 667–675 (1979). https://doi.org/10.1038/bjc.1979.118
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DOI: https://doi.org/10.1038/bjc.1979.118