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Augmentation of cytotoxic drug action and X-irradiation by antibodies

British Journal of Cancer volume 32, pages 352–354 (1975)Cite this article

Abstract

The effect of an antiserum containing antibodies against cell surface components of PyBHK cells on the action of certain anticancer agents has been studied using a colony formation inhibition assay. The effects of x-rays, chlorambucil, CCNU and possibly ICRF 159 are augmented by the antiserum whereas methotrexate and vinblastine are not.

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Authors
  1. R D Rubens
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  2. S Vaughan-Smith
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  3. R Dulbecco
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Rubens, R., Vaughan-Smith, S. & Dulbecco, R. Augmentation of cytotoxic drug action and X-irradiation by antibodies. Br J Cancer 32, 352–354 (1975). https://doi.org/10.1038/bjc.1975.234

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  • DOI: https://doi.org/10.1038/bjc.1975.234

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