Correction for “Thiazolidione derivatives targeting the histidine kinase YycG are effective against both planktonic and biofilm-associated Staphylococcus epidermidis” by Huang RZ, Zheng LK, Liu HY, Pan B, Hu J, Zhu T, et al, which appeared in issue 3, 2012, of Acta Pharmacol Sin (33: 418–25; first published online Jan 9, 2012; 10.1038/aps.2011.166).

In Figure 3, the H2-27 part was incorrect, the correct Figure 3 and legend should be

Figure 3
figure 1

Bactericidal effects of the derivatives on mature S epidermidis biofilms. S epidermidis ATCC 35984 was grown in cover-glass cell-culture dishes at 37 °C for 24 h. Subsequent to the removal of planktonic cells, the 24-h-old biofilms were further incubated at 37 °C for another 16 h with fresh TSB containing the following substances: 0.1% DMSO, 128 μg/mL vancomycin, 24.3 μg/mL H2-10, 26.1 μg/mL H2-12, 24.7 μg/mL H2-20, 13.1 μg/mL H2-29, 12.4 μg/mL H2-27, or 12.4 μg/mL H2-28. After incubation, the biofilms on the dishes were washed with normal saline and stained with Live-Dead reagents (containing SYTO9 and PI), and observed under CLSM using a 63×objective lens. Images representative of the results from three independent experiments were three-dimensionally reconstructed using Imaris software based on CLSM data at approximately 0.5 μm increments. The green fluorescent cells are viable, while red fluorescent cells indicate dead bacteria.

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The authors and editors are sorry for this error.